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5 Emerging diagnostic biomarkers and predictive tools 5.1 Genetic and transcriptomic biomarkers Genetic and transcriptomic biomarkers, particularly epigenetic regulators, have emerged as critical indicators for predicting endometriosis and associated infertility risks by modulating endometrial receptivity, decidualization, and implantation processes

Traditional clinical trials often miss rare or long-term side effects due to limited follow-up and participant diversity

Taking into account the above-mentioned considerations on cost and safety aspects, oral small molecule agonists stimulating endogenous GLP-1 secretion by intestinal L-cells may offer a promising alternative for developing new treatments for Type 2 diabetes and obesity

Gastrointestinal side-effects are common - the clinical trials and the real world data tells us around 80% of people get GI side effects - especially at the start of GLP-1 treatment or after increasing the dose

Symptoms typically resolve within 48 hours and diminish significantly after the first month of consistent dosing