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The toxicity of free heme is implicated in the pathology of the various etiologies of hemolytic disorders (hemolytic anemias, hemorrhagic strokes and traumas, malaria, sepsis, ischemia reperfusion injury and others [217])
This evolving perception is helping the product transition from a niche traditional drink to a globally relevant option within the health and wellness beverage category
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On the one hand, this would exclude the possible nonspecific contribution of the additional volume (applied to induce ischemia [174,175,176,177,178,179])