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A landmark, randomized, double-blind renal health study: reduces the risk of major kidney disease events by 24%, 50% greater decline in eGFR or death from renal/CV causes reduces cardiovascular (CV) events by 18%, and 20% reduction in all-cause mortality in patients with type 2 diabetes and chronic kidney disease

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Will this impact prescribing or refill processes

Meszaros and Pappano, 1990

Potential selection criteria might include: Adolescents with BMI 95th percentile for age and sex History of unsuccessful comprehensive lifestyle interventions Presence of obesity-related comorbidities Absence of contraindications (eating disorders, severe mental illness) Adequate family support and resources for monitoring Informed consent and assent processes completed Monitoring and Follow-up Comprehensive monitoring protocols are essential for safe and effective use of GLP-1 RAs in adolescents