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We employed an adeno-associated virus vector (AAV2/8) to deliver and express either human wild-type hepsin (hHPN WT
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In both studies, bone mineral density (BMD) didnt really change across treated and conservative groups, but there were significant reductions in the incidence of new vertebral fractures in surgically treated groups in both studies. He further notes that the diagnosis and management of these patients remains challenging: more so the unresolved issue of whether dysregulated cortisol secretion plays any pathogenetic role in what could easily be age-related comorbidities
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