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These studies presented several limitations, in fact, they did not adjust for potential confounding variables such as genetic factors, sun exposure, vitamin D intake

doi:10.1210/clinem/dgz069 28

The compound also slows gastric emptying, meaning food stays in your stomach longer, providing sustained fullness without the blood sugar spikes that often trigger cravings

Similarly, SURMOUNT 3 showed a mean BW reduction of 18.4% with tirzepatide titrated to the maximum tolerated dose (15 mg for 86% participants) after a 72-week follow-up 35