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The 48-week phase 2 results (24.2%) already exceeded what Mounjaro accomplished at 72 weeks (22.5%)

Singh says some people will experience palpitations if their system is lacking certain nutrients

Fatigue or Dizziness Some individuals report temporary fatigue, lightheadedness, or low energy early during treatment

But Lange called that "a theoretical concern" and pointed to evidence showing that it is "not a true limitation." For example, he said patients were treated with the pill for up to five years in the placebo-controlled SOUL trial and "even in that setting, we did not see this as a limitation." "Patients take that drug apparently without this limiting their life," Lange said

[99] A person with cobalamin C disease, a rare autosomal, recessive, inheritance disease which results in combined methylmalonic aciduria and homocystinuria), [100] can be treated with intravenous or intramuscular hydroxocobalamin