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The abdomen (stomach), upper thigh, and upper arm are the Mounjaro injection sites

That means sterile water is only appropriate for single-use applications where the entire contents are used immediately

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OxPhos is achieved in the presence of saturating ADP levels and the sequential addition of different mitochondrial substrates, including pyruvate, malate, glutamate (N-linked, through complex I) and succinate (S-linked, through complex II)

Resulting adducts were analyzed using bottom-up proteomics, with or without LC fractionation prior to LC-MS/MS analysis on a quadrupole-time-of-flight instrument with data-dependent acquisition (DDA)