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doi: 10.1038/s44321-024-00190-3 26 BindocciE.SavtchoukI.LiaudetN.BeckerD.CarrieroG.VolterraA.et al

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This reduction in SLC25A3 expression impaired the electron transport chain by decreasing copper in mitochondria, leading to electron leakage and increased mitochondrial ROS production