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In its decision, the regulator told Citius it would need to incorporate enhanced product testing and additional controls that were agreed to during the market application review

A BMI of 30 is typically used as a cutoff for obesity, while 25 is used as the cutoff for overweight

it does not decide whether any specific plaintiffs injury was caused by a drug

In addition, it is important to remember, that the ability to utilize the transporter does not guarantee a high extent of brain delivery, which should be evaluated in pharmacokinetic studies (79)