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[3] [6] In the context of aging skin, oxidative damage and low-grade inflammation are plausible contributors to matrix degradation, so an agent that modulates both is mechanistically attractive

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These include pancreatitis, an inflammation of the pancreas that can be severe and life-threatening

PMID: 35220312 Wang X, Wang Z, Cao J, Dong Y, Chen Y (2023) Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation