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Back Capozzi, ME, DiMarchi, RD, Tschp, MH, et al (13 June 2019) Targeting the incretin/glucagon system with triagonists to treat diabetes', Endocrine Reviews , 39/5, 719-38

Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects

These findings represent substantial improvements over traditional anti-obesity medications and approach the efficacy levels historically associated with bariatric surgery

Discussion Most animal studies demonstrated a beneficial effect of GLP-1RAs and related peptide polyagonists on LFTs, glucose, and lipid metabolism and, most importantly, on hepatic steatosis and inflammation (Tables 1 and 2)

titled Comparative Pharmacology and Abuse Potential of Oral Dexamphetamine and Lisdexamfetamine , published in Human Psychopharmacology (2024), Vyvanse overdose primarily results from its potent effects on the central nervous system, which overwhelm the body when misused