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[15] Semaglutide is a peptide similar to the hormone glucagon-like peptide-1 (GLP-1), modified with a side chain, and acts as a GLP-1 receptor agonist

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When switching to tirzepatide might make sense Tirzepatide (brand name Mounjaro/Zepbound) is a dual GIP/GLP-1 receptor agonist that has shown greater weight loss than semaglutide in head-to-head trials