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He concluded that harmonization would be difficult to achieve given the different positions of the Member States and the scientific issues that must first be resolved (Coppens, 2018)

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Figure 3 The effect of treatments on cysteine metabolism The combination of mB12/LDFA significantly increased total Cysteine [ F (1, 57) = 6.26, p = 0.01

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Missense variants involve substituting a single amino acid, resulting in a protein with reduced or different functionality