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GLP-1 agonists work in several ways, such as by: stimulating meal-dependent insulin secretion by the pancreatic beta cells decreasing the secretion of glucagon, a hormone that raises blood sugar decreasing gastric emptying decreasing appetite and reducing food intake by creating a sensation of stomach fullness GLP-1 agonists may also have some direct effects on brain hunger centers

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However, several considerations must be taken into account

Approved by the FDA in 2004, acamprosate is prescribed after alcohol detox to prevent relapse, not to treat withdrawal symptoms