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In Vitro GSH Skin Permeation Tests To investigate the ex vivo permeation kinetics across the skin of the reduced-GSH released from the GSH 2.5 -HA MN patches, static diffusion Franz cell tests were performed to calculate the rate of time-dependent GSH release through GSH 2.5 -HA MNs and its diffusion through the skin along with a reference GSH-HA solution