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Unfortunately, this compensatory surge is futile because the downstream clearance pathwaysspecifically the enzymes mitochondrial superoxide dismutase (SOD2) and glutathione peroxidase 4 (GPX4)are severely dysfunctional

Derosa, G., Cicero, A

Placebo capsules comprised microcrystalline cellulose (REDWELLS HEALTH LTD, London, UK) combined with 10% (w/w) gum Arabic (CAS 9000-01-5, Willy Benecke, Hamburg, Germany), matching the gum Arabic content of the pomegranate extract, and 1% (w/w) brown food coloring (rainbow dust edible powder color, Cake Decorating Co., UK) to ensure that the pomegranate and placebo capsules were identical in appearance

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