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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

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and subsequently to activate the thiol group of GSH, enabling the nucleophilic attack upon the substrate

Sequencing libraries were prepared using the SMARTer Stranded RNA-Seq Kit (Clontech Laboratories, Inc., USA) and the Poly(A) RNA Selection Kit (LEXOGEN, Inc., Austria) by the manufacturers recommendation