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Consistent subcutaneous delivery provides the most predictable pharmacokinetic profile

While both groups had similar rates of adverse events (89% in the liraglutide group and 88% in the placebo group), the liraglutide group reported a higher incidence of gastrointestinal side effects due to dose escalations, however, none resulted in hospitalization

Clinical Response In both studies, patients treated with TALTZ 80 mg Q4W demonstrated a greater clinical response including ACR20, ACR50, and ACR70 compared to placebo at Week 24 (Table 6)

The FDA position on prefilling The FDA has issued guidance discouraging healthcare facilities from prefilling syringes outside of pharmacy-controlled environments

cDNA was generated from total RNA using the High-Capacity cDNA Reverse Transcription Kits (Applied Biosystems)