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While APEX2 and HRP both showed BP labeling on the cell surface and in the ER lumen, LaccID was exclusively active on the cell surface, with no labeling detected from ER-targeted LaccID (Fig

Since the turn of the millennium, numerous electrophilic warheads have been developed, with a significant number of functional groups available for covalent labelling 15

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d For STEP 1, the presence of prediabetes was determined by investigators based on available information (e.g