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Once activated by upstream kinases through T172 phosphorylation, AMPK further phosphorylates specific substrates to inhibit lipid and protein synthesis and stimulate glucose uptake, fatty acid oxidation (FAO) and mitochondrial and lysosome biogenesis 6 , collectively maintaining energy and redox homeostasis 7

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Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF- induced epithelial to mesenchymal transition