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Neuroprotective Studies MC1R activation influences AMPK, SIRT1, and PGC-1 pathways that regulate mitochondrial metabolism

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This reactivity is its greatest strength in a biological system

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Experiments conducted using a polyacrylamide-based microchannel device that allows independent control of substrate stiffness and channel dimensions revealed that optimal migration of triple-negative MDA-MB-231 and SUM159 human breast cancer cells occurs at intermediate stiffness [90]

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