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The number of doses stays the same

Wegovy also showed a favorable safety profile

IGF-1 LR3 functions through direct, sustained agonism of the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating the same downstream intracellular signalling cascades as native IGF-1 but with substantially reduced IGFBP-mediated attenuation and a far longer biological activity window

219 Elevated Ca 2+ stimulates PTHrP secretion and activates RANKL/RANK signaling in osteoclasts, which promotes bone resorption and calcium release, in turn promoting tumor cell proliferation and maintaining PCa cell homing to bone

Randow, R