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A systematic review and meta-analysis of cardiovascular outcomes trials

The gastrointestinal effects are generally dose-dependent, meaning higher doses are associated with increased likelihood and severity of symptoms

Liraglutide (2 mg/kg) reduced immune cell infiltration and protein expression of E-selectin, TNF- , IL-4, IL-5, and IL-13 in the lung tissue or bronchoalveolar lavage fluid in an ovalbumin-induced chronic asthma model

N Engl J Med 375(19):18341844 Marx N, Husain M, Lehrke M, Verma S, Sattar N (2022) GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes

Under normal physiological conditions, the fed state leads to increased circulating glucose, which stimulates the secretion of insulin from pancreatic -cells