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Depakote) to sodium valproate Foetal malformations Sodium valproate is generally well tolerated compared to other anti-convulsants with low toxicity and lack of sedative effect, however its use is restricted in males and females (of childbearing age) due to a high risk of feotal malformations

TB-500 has a longer half-life and distributes systemically, providing sustained background activity between the twice-weekly doses

Images were collected using the 365 nm (DAPI) and 488 nm (Alexa-488) channels on a Zeiss LSM confocal microscope by sequential line scanning

Neganova, M., Liu, J., Aleksandrova, Y., Klochkov, S., Fan, R., & Dec (2021)

3,265,266 Classical and non-classical congenital adrenal hyperplasia (CAH and NC-CAH) are autosomal recessive diseases that cause adrenal steroid 21-hydroxylase deficiency