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Both have their place, and they are not mutually exclusive

Research models have observed DSIPs interaction with pathways associated with cortisol regulation, neurotransmitter balance, and adaptive stress response, highlighting its relevance in sleep and cognition-focused research

Medical monitoring is important during treatment to minimise complications

That said, this is not a do-it-yourself situation

Microglia can be artificially activated by LPS, which induces a switch from a protective to pro-inflammatory state with the production of IL-12, TNF, NO, superoxide anions, and peroxynitrite (H 2 O 2 ), causing motor neuron degeneration and exacerbation of disease progression in fALS mice [124126]