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Emerging researches emphasize the complex interactions between environmental stressors and systemic physiological adaptations, by focusing on oxidative stress/antioxidant defense mechanisms, mitochondrial energy metabolism, immune system modulation, and neuroendocrine equilibrium

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While researchers found that GLP-1 drugs collectively showed positive impact on managing type 2 diabetes by effectively lowering haemoglobin A1c and fasting plasma glucose levels, higher doses of these drugs were shown to significantly increase adverse gastrointestinal reactions