After 108 weeks, changes in UACR from baseline with lixisenatide were 1.69% [(95% CI: 11.69 to 8.30), p=0.7398] in patients with normoalbuminuria, 21.10% [(95% CI: 42.25 to 0.04), p=0.0502] in patients with microalbuminuria, and 39.18% [(95% CI: 6853 to 984), p=0.0070] in patients with macroalbuminuria
Severe nausea warrants immediate contact with your PlexusDx provider, who may recommend extending your stay at the current dose, adjusting meal timing and composition, or temporarily reducing your dose
A dose should be judged by whether it maintains the agreed weight range, controls appetite appropriately and allows adequate nutrition with acceptable side effects
How Weight Loss Treatment Works: The Science Your body weight is regulated by your brain, hormones (leptin, ghrelin), gut, and fat cells a system evolved to defend against weight loss
That means it works through two pathways instead of one, which may lead to greater weight loss for some patients