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Importantly, tirzepatide carries a boxed warning for risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), and is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Subcutaneous soft tissue tumours at the site of implanted microchips in mice

A flurry of other studies published recently show relatively high percentages of patients dropping out as early as four weeks into treatment and that discontinuation increases over time

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While it may be tempting to cease treatment once weight loss goals are achieved, semaglutide also helps maintain weight loss and manage diabetes symptoms