One drug isnt better than the other, but semaglutide (the active ingredient in Wegovy and Ozempic) targets a single potent pathway (the GLP-1 receptor), while retatrutide is a triple-agonist, acting on GLP-1, GIP, and glucagon receptors
This selectivity is frequently framed in the literature as a comparative advantage over earlier GHRP-family compounds
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For physical symptom management , consider omega-3 fatty acids to reduce inflammation and NAC to enhance glutamate clearance