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Despite the central role that articular cartilage, synovium, synovial fluid, and menisci play in OA research, there are still some limitations in current studies

The blots were washed and then incubated with a secondary antibody conjugated to horseradish peroxidase (Jackson ImmunoResearch Laboratories, West Grove, PA, USA), and the blots were visualized using a western blotting luminol reagent kit (Santa Cruz Biotechnology, Santa Cruz, CA.)

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Bakin A.V., Stourman N.V., Sekhar K.R., Rinehart C., Yan X., Meredith M.J., Arteaga C.L., Freeman M.L

GA decreases the activity of catalase (CAT), ascorbate peroxidase (APX), and superoxide dismutase (SOD), leading to reduced scavenging ability for ROS, consequently resulting in peroxidative damage of membranes followed by release of hydrolytic enzymes (Jones and Smirnoff, 2005