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Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides

The decreased NADPH production results in insufficient reduction of oxidized glutathione disulfide (GSSG) and Prdx2, thus rendering the antioxidant system less effective (20)

They may protect against atherosclerosis by suppressing angiotensin II-induced vascular smooth muscle cell proliferation via inhibition of intracellular ROS production, calcium ion mobilization, pkc- expression, ERK1/2 phosphorylation, and proto-oncogene expression (46)

This finding, taken with the available information on -ECS and GSH-S localization, leads to the view that the synthesis of -EC is restricted to the plastid but that GSH synthesis can also occur in the cytosol following -EC export across the plastid envelope (Wachter et al., 2005

Media was changed once every 23 days and supplemented with 1 g ml 1 laminin weekly to promote cell attachment