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Interesting fact: vitamin B12 was isolated, crystallized, and characterized in the laboratory of Dorothy Hodgkin, contributing to her Nobel Prize in 1964. 1 Vitamin B12, also called cobalamin, plays a key role in the formation of DNA and red blood cells, and in maintaining healthy brain and nerve cells

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7.1.1 Use of cytokine inhibitors Cytokines, particularly pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF- ), interleukin (IL)-1, and IL-6, are known to contribute significantly to BBB dysfunction and neuroinflammation following I/R injury (Jurcau and Simion, 2021)

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