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Its 28-day usability window after opening is specifically designed for this use case, and using sterile water in a multi-dose context introduces a real and unnecessary contamination risk with every additional needle insertion

When given orally, semaglutide is dosed differently as absorption and delivery are different from injectable semaglutide (more on that below)

Evening administration is as pharmacologically neutral as morning dosing

If your lab can measure this, it might be the single best way to fine-tune your dose

The commenter also noted that 1 month after C1747 was established based on the approval of the STERIS Uretero1 TM device pass-through application, FDA granted the LithoVue TM Elite System 510(k) clearance, on February 2, 2023