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Vitamin B12 absorption occurs primarily in the terminal ileum through intrinsic factor-mediated absorption (for both dietary and supplemental B12) and passive diffusion (particularly relevant for high-dose supplements)

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Our finding showed that circulating MMA level was independently associated with all-cause death and cardiovascular mortality risk in patients with CHD, while serum B12 concentration, dietary B12 intake from food and B12 supplements use were not significantly associated with mortality risk

Pan-cancer analysis through TIMER2.0 and ImmuCellAI databases revealed a significant negative correlation between Kla score and NK cell infiltration, particularly in adrenocortical carcinoma, uterine carcinosarcoma, and endometrial carcinoma, among others

95% CI: 0.540.93