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It acts as an agonist at glucagon-like peptide-1 receptors, glucose-dependent insulinotropic hormone receptors, and glucagon receptors

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This implies that lactate is neuroprotective in our model of the ischemic penumbra, and that this beneficial effect is mediated by the transport and metabolism of lactate in neurons

Once accurately placed, the cannula was secured to the skull with cyanoacrylate adhesive

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However, this effect is transient and reversed upon discontinuation of therapy, and the long-term risk-benefit analysis of its administration is still unclear