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10.1038/s41419-021-03952-w 57 GuoJ.WangR.LiuD

Journal of Plant Physiology

The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide

Growth hormone receptor upregulation GH-R expression on tendon fibroblasts is increased, potentiating the local anabolic response to circulating IGF-1