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3 Results 3.1 Effects on overweight/obesity Obesity has been identified as a chronic disease linked to increased mortality, coronary artery disease, T2DM, some types of cancer, and many other complications (2931)

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3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance