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WD increased weight gain and plasma leptin levels and reduced PSD95 in the amygdala in both sexes, whereas GE2 treatment induced weight loss, elevated plasma PYY levels, and improved associative learning in both sexes

Retatrutide is not yet licensed by the MHRA or EMA and remains unavailable outside approved clinical trials in the UK

Microdosing semaglutide could be a good option for individuals who are sensitive to the side effects of higher doses or those who are looking for gentle, gradual weight loss

Ischemic heart disease A randomised controlled trial examined the effects of sauna use in 24 patients with ischemic heart disease with chronic total coronary artery occlusion (full blockage of one or more of the arteries that supply the heart) who had not responded to non-surgical procedures and were not candidates for surgical interventions

Upcoming Study AgelessRx plans to commission a study aimed to explore various discontinuation strategies and their effectiveness in maintaining weight loss