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Animal studies confirm: offspring of caffeine-exposed rats showed abnormal methylation patterns on genes controlling adrenal hormone production, with 51.2% born growth-restricted.[28] Most alarming: these epigenetic effects carried forward into grandchildren never exposed to caffeine themselves.[17] Your Genes Determine Your Risk The CYP1A2 gene has a well-studied polymorphism (rs762551)

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The 2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion

90 As such, this molecule has been investigated keenly for its role in carcinogenesis, tumor progression, invasion, angiogenesis, and other key biological processes

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