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1 and 2).38 Screening of melanin pigmentation using Fontana-Masson staining identified residual melanin in 16% of vitiligo cases, and in 12% of cases, melanocytes were identified in the lesions, demonstrating that total destruction of melanocytes may not occur in the affected area.38 On electron microscopy, abnormal melanogenesis was identified in active vitiligo
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Evan Thacker: nothing to disclose
The absence of biotin affects the expression of transcription factors like NF-B and SP1/3, indicating that biotin regulates immunological phenomena via mechanisms besides carboxylation and decarboxylation (152) ( Table 2 )
