Finally, arGLP-1 has been shown to improve the pre- and postprandial lipid profile, with a reduction in the levels of free fatty acids, triglycerides and LDL cholesterol, as well as the fraction of small and dense LDL and a reduction of the increase levels of triglycerides and apo-B48 postprandial.7882 Likewise, it has been reported a reduction in markers of inflammation, plasminogen activator inhibitor type 1 and leptin whereas adiponectin levels increase.47,48 Regarding the adverse effects of this family, the most important are gastrointestinal, especially nausea and vomiting of mild-moderate intensity, which are reduced with time
A great example of innovation translating basic science into real-world therapeutic benefit
Alcohol plus insulin plus reduced food intake plus delayed gastric emptying is a stack of factors all pushing blood glucose in the same direction
And just as importantly, what should patients do when their progress suddenly stalls, even while still on the medication
10.1016/j.cmet.2013.04.008 24 ChallaT
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