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Tricyclic antidepressants TCAs are thought to relieve pain by inhibiting the reuptake of noradrenaline and serotonin in presynaptic neurons and by antagonizing N-methyl-D-aspartate receptors, which mediate hyperalgesia and allodynia [52-54]

In a metaanalysis a negative association was also found between high bilirubin levels and severity of atherosclerosis (37)

Redox Biol 75:103283