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In BV2 cells, the inflammatory factor IL-6 was upregulated after FAC exposure, in turn, DMT1 was upregulated and FPN1 was downregulated following 24 hours of IL-6 stimulation, which resulted in iron overload ( Oxidative stress and autophagy were reported to participate in microglial ferroptosis likewise

Cancer 109(1):125-34, 2007

The inflammatory response is modulated by diet composition, aging, and microglial priming, and exhibits marked sexual dimorphism, with males typically displaying a more pronounced pro-inflammatory response and females showing relative resilience

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Topical application reduced wound size by 64.5% over 13 days, compared to 45.6% in the vehicle-treated group and 28.2% in controls