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In 1857, Virchow formally put forward the concept of melanosis coli.7 MC is becoming increasingly common because there are many pathological conditions of the bowel that prompt the use of anthraquinone laxatives.8 To promote a better understanding of MC, we will summarize the recent progress made in MC research

These may include nausea, reduced appetite, vomiting, diarrhea, constipation, abdominal discomfort, or reflux