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On a reassuring note, post-marketing data and clinical trials have found no link between GLP-1 agonists and suicidal behavior, suicidal thoughts, self-harm, or depression

For the research context it expanded the perspective from pure longevity to specific clinical indications , especially neurodegenerative diseases, where mitochondrial dysfunction and NAD+ deficit play a central role

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Live cell imaging results showed that some cells exhibited a state of non-division or nonextension under Gln deficiency (Gln) conditions, whereas cells grew plum and well under Gln sufficiency (Gln+) conditions (Fig