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Furthermore, a deficiency in zinc markedly impairs the barrier function of porcine endothelial cells [471], making them more prone to leukocyte infiltration and facilitating inflammatory processes [472]

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Following biological evaluation, molecule 49 (Figure 6) was selected as the hit compound from which compounds 50 and 51 were designed

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BPC-157 may allow faster progression through these stages, but each stage should still be completed