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In-depth studies of the intricate relationships between oxidative stress and various forms of cell death in vitiligo are expected to provide crucial insights into the mechanisms underlying melanocyte loss

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The drug was also well tolerated, with mostly mild or moderate gastrointestinal-related adverse events that Roche said were "consistent with the safety profile of the incretin drug class," and will now progress to phase 2

Summary: Dark urine on Ozempic typically results from dehydration caused by gastrointestinal side effects such as nausea, vomiting, and diarrhoea, leading to concentrated urine rather than being a direct drug effect