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Using rational drug design, we synthesized and tested the 45 amino acid monomeric chimeric peptide EP45 that contains the partial amino acid sequences of exendin-4 and PYY(336) at its N- and C-termini, respectively (Fig
This albumin-engineering strategy was also effective when applied with a therapeutic fusion partner, glucagon-like peptide 1 (GLP-1), resulting in a 2-fold increase in plasma half-life and prolonged efficacy in human FcRn transgenic mice
Four-hour acetaminophen concentration estimation after ingested dose based on pharmacokinetic models
Our preliminary data also suggest that GHK increases the expression of p63 and PCNA in primary lung fibroblast cultures from aged mice
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