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26 In females newly diagnosed with Graves disease, vitamin D level was negatively associated with thyroid volume and found to be significantly lower than in a disease-free control group, with a prevalence of vitamin D deficiency of 65.4% in the Graves disease group, compared to 32.4% in the control group

There are some indications that IGF-1, unlike insulin, may not affect lipogenetic activities of insulin and the down-r3egulation of insulin receptors and also atherogenetic processes to the same extent as insulin