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Underlying mechanisms may involve microbial-mediated drug metabolism, transformation, and modulation of intestinal barrier function

Carnitine palmitoyltransferase I (CPT I) then catalyzes the formation of fatty acyl-carnitine, which is transported across the mitochondrial membrane

in: PubMed | Google Scholar | Authorship note: MAS and DM contributed equally to this work

Looking forward: There is increasing pressure on drug companies to lower costs and insurance companies to cover GLP-1 RAs for obesity or overweight with a weight-related condition

The results of our analyses support and augment these published data to provide evidence of benefit upon treatment switch in various subgroups at different time points